Scientists at the Queen Mary University of London and Imperial College developed BioMinF, a new toothpaste ingredient that restores minerals from tooth enamel, treats sensitivity, and prevents tooth decay during sleep. The toothpaste with this ingredient slowly releases phosphate, fluoride ions, and calcium over a period of eight to 12 hours to form the fluorapatite that repairs teeth, therefore providing relief from the most prevalent disease in the world.

“Using remineralising toothpaste makes teeth far more resistant to attack from acidic soft drinks like fruit juices and sodas,” explains lead researcher Robert Hill, chair of Dental Physical Sciences at the Queen Mary University of London. “It is also much more effective than conventional toothpaste where the active ingredients, such as soluble fluoride, are washed away and become ineffective less than two hours after brushing,”

“Tooth sensitivity is caused by open tubules in the teeth allowing access to the nerve receptors which may affect the quality of life of individuals particularly when eating and drinking hot and cold food and drink,” adds David Gillam, an expert of dental hypersensitivity management, as well as a consultant and co-founder of BioMin. “BioMin containing toothpaste are effective by sealing the tubules with acid resistant fluorapatite which act as a barrier to hot and cold being transmitted inside the tooth.”


A healthcare worker teaches a child how to brush her teeth. Photo from Wikimedia/Staff Sgt. David Gillespie

A 75ml tube of BioMin is available online for £4.99 or AU$9.32. A fluoride-free version is currently under development.

However, Hill points out that the technology behind the ingredient not only acts as a toothpaste to prevent tooth decay. Apparently, BioMinF can also be used in other dental products used only by professionals, including varnishes, cleaning and polishing pastes as well as remineralising filling materials.

The researchers hope to commercialise the technology. “We are very excited by the prospects of developing the patented technology which has been licensed from Queen Mary University of London and Imperial College. We are in the process of establishing licensing agreements with toothpaste and dental materials manufacturers around the world,” said CEO Richard Whatley.