The much-awaited mid-season premiere of “Grey’s Anatomy” season 12 is happening tonight (Feb 11).

Warning! Five major spoilers for this season are mentioned here.

1. Dr Meredith Grey’s will face another life-or-death situation – this time, it will involve a patient who will attack her brutally.

Design & Trend wrote Meredith will start her day at Grey-Sloan Memorial Hospital like any other until she will come across a very angry, agitated, and violent patient.

2. Will her colleague able to save her life?

Yes, they will. However, “Grey’s Anatomy” actress Caterina Scorsone, who plays Dr Amelia Shepherd, said the attack on Meredith will have a “long-term” impact on the character’s life.

Scorsone told TV Guide: “The attack itself is shocking. It’s quite brutal, and the damage is extensive. It’s not just a couple bruises… It’s a pretty long-term situation. Meredith is the person who gets attacked, but it does impact everyone quite profoundly because she’s such a central person in the constellation of relationships at the hospital.”

3. Can we expect see Dr. Cristina Yang in the series?

Viewers are hoping to see Yang, played by Sandra Oh, even if for only an episode or two. However, it seems unlikely considering Yang did not show up when her friend and Meredith’s husband, Dr Derek Shepherd died.

Who knows? Yang may come back for her “person”.

4. Entertainment Weekly reported that in this season Jackson Avery (Jesse Williams) and April Kepner (Sarah Drew) will hit the rewind button on their relationship.

5. Sexy sexy is back.

Jason George, who portrays Dr Ben Warren on “Grey’s Anatomy,” told People magazine that the series writers are looking at a fresh take for the upcoming season.

“They’ve hit reboot almost. There’s a lot of things that make it feel brand new, but it has that lightness and sense of humor that people fell in love with in the first place,” George said.

“And the sexy is back on. There are a lot of people who are not in couples now and are falling into bed. Everyone’s getting a little bit of loving,” he added.