Magic mushrooms could be a strong cure to severe depression as a number of clinical trials found it lifting depression in patients. The mushrooms have a hallucinogenic compound, Psilocybin which is claimed to successfully cure depression in untreatable patients.

The new revelation appeared in a study published in The Lancet.  Scientists from the Imperial College London gathered 12 people (6 men and 6 women) and gave them a regulated dosage of the compound. Initially, all of them were given two oral doses of psilocybin of 10 mg and 25 mg, seven days apart.

After giving the patient their dose, researchers noticed the compound’s psychedelic effect in 30 to 60 mins. It was well received by the patients and didn’t hurt the patients seriously. All of them, on average, had been depressed for around 17 years. Standard medications like serotonin re-uptake inhibitors (SSRIs) didn’t give satisfying outcome to patients before.

There were some adverse symptoms noticed like transient anxiety, confusion or thought disorder, mild and transient nausea and headache. But at the same time, the researchers also noted a reduction in depressive symptoms which were noticeable in the first week. And it improved following a high dose in the next three months.

“This study provides preliminary support for the safety and efficacy of psilocybin for treatment-resistant depression and motivates further trials, with more rigorous designs, to better examine the therapeutic potential of this approach.” reports the study.

According to Telegraph, the researchers found the trials promising, but not fully convincing. They are looking to carry out more trials. For that, they are expecting funds from Medical Research Council and other bodies.

Robin L Carhart-Harris, one of the authors of the study, advised the public not to use Psilocybin by themselves.

“Psychedelic drugs have potent psychological effects. They are only given in our research when appropriate safeguards are in place such as careful screening and professional therapeutic support,” said Earhart-Harris in a report by RT.

“I wouldn’t want members of the public thinking they can treat their own depressions by picking their own magic mushrooms. That kind of approach could be risky,” he added.